FROM PARTICIPATORY CULTURE TO PARTICIPATORY FATIGUE: THE PROBLEM WITH THE PUBLIC


Variation in one residue associated with the metal ion-dependent adhesion site regulates αIIbβ3 integrin ligand binding affinity.

The Asp of the RGD motif of the ligand coordinates with the β I domain metal ion dependent adhesion site (MIDAS) divalent cation, emphasizing the importance of the MIDAS in ligand binding.There appears to be two distinct groups of integrins that differ in their ligand binding affinity and adhesion ability.These differences may be due to a specific

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